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Study of Revascularization of Autogenous Cortical Bone Grafts in Rabbit Using Radiophosphorus
ALBERT B. FERGUSON, Jr., M.D.;
PATRICK G. LAING, M.D.;
MARY GREBNER, B.S.;
LAVERNE MADANCY, B.S.
AMA Arch Surg. 1959;78(4):551-555.
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This study was undertaken in an attempt to evaluate the fate of various types of autogenous cortical grafts in the rabbit by a somewhat different method than those usually employed. The influence of the physical form of the graft is shown, as well as the deterrent effect of fibrous periosteum as a barrier to revascularization. The effect of using a motor-driven saw rather than a osteotome is also shown.
Cohen et al.3 have used Ca45 as an indicator of homogenous bone-graft fate. Kiehn et al.7 have used phosphorus for the purpose of comparing the incorporation of autogenous bone grafts into the host. Evaluation of bone grafts from a histological point of view have demonstrated the difficulty inherent in determining the end-point by this means. Each microtome section shows only a small part of the graft and host; the interpretation is often tedious and controversial. The uptake of
. . . [Full Text PDF of this Article]
Author Affiliations
Pittsburgh
From the Department of Orthopedic Surgery, University of Pittsburgh School of Medicine.
Footnotes
Submitted for publication Oct. 7, 1958.
This work was supported by a grant from the Western Pennsylvania Chapter of the Arthritis and Rheumatism Foundation.
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