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WILLIAM SILEN, M.D.; WILLIAM H. BROWN, M.D.; BEN EISEMAN, M.D.

AMA Arch Surg. 1959;78(6):897-903.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Most surgeons are unaware that patients with pulmonary emphysema have an inordinately high incidence of peptic ulceration and that these ulcers are of a peculiarly complicated and resistant nature. This paper is a review of the incidence of peptic ulcer in our own Emphysema Registry, an investigation of gastric secretory activity in 20 patients with marked emphysema, and a study of pathogenic factors that may relate to the two conditions. The clinical implications of these findings are discussed.

I. Frequency of Coexistence of the Diseases

A. Incidence of Peptic Ulcer in Patients with Emphysema.

—Green and Dundee,¹ in 1952, found a 19% incidence of ulcer in both a clinical and an autopsy series of patients with proved emphysema. In a similar study, Flint and Warrack² found a 21% incidence of peptic ulceration in 87 autopsy patients with proved emphysema, as compared with an incidence of 1.6% in a . . . [Full Text PDF of this Article]

Author Affiliations
Denver

From the Department of Surgery, University of Colorado School of Medicine, and the Denver Veterans Administration Hospital.

Footnotes
Supported in part by USPHS Grant No. H-3872.

Read at the 66th Annual Meeting of the Western Surgical Association, Rochester, Minn., Nov. 22, 1958.

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