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The Treatment of Cancer by Perfusion
OSCAR CREECH, Jr., M.D.;
E. T. KREMENTZ, M.D.;
R. F. RYAN, M.D.;
KEITH REEMTSMA, M.D.;
J. N. WINBLAD, M.D.;
JAMES L. ELLIOTT, M.D.
AMA Arch Surg. 1959;79(6):963-975.
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Technique
Technique
Figure 3
Figure 4
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Figure 6
Technique
Figure 7
Figure 8
Figure 9
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Metastatic Melanoma
Fig. 11.—Before perfusion.
Fig. 12.—Two years after perfusion.
CASE 1.
—A 77-year-old white man. In 1956 malignant melanoma removed from left foot, followed by groin dissection May, 1957: Appearance of multiple dermal metastases. June, 1957: Isolated perfusion with 120 mg. phenylalanine mustard (PAM) through common femoral artery.
Fig. 13.—Original lesion.
Fig. 14.—Metastasis, six weeks after perfusion.
Fig. 15.—Metastasis, eight weeks after perfusion.
Melanoma
Figure 16
CASE 2.
—1947: Small mole (malignant melanoma) removed from right medical lower leg. 1958: Local recurrence followed by multiple excisions. Treated with TSPA intra-arterially without improvement (Fig. 16, A). December, 1958: Common femoral artery perfusion with 130 mg. PAM (1.8 mg. per kilogram of body weight). January, 1959: Many lesions disappeared (Fig. 16, B).
Figure 17
CASE 3.
—1957: Malignant melanoma with extensive metastases
. . . [Full Text PDF of this Article]
Author Affiliations
New Orleans
Tulane University School of Medicine; Charity Hospital of Louisiana; Touro Infirmary; U.S. Public Health Service Hospital.
Footnotes
Received for publication Aug. 14, 1959.
Surgery Illustrated. Shown as a scientific exhibit of the Section on Surgery, General and Abdominal, at the 108th Annual Meeting of the American Medical Association, Atlantic City, June 8-12, 1959.
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