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BASED ON A STUDY OF ONE HUNDRED AND THIRTY XANTHOMATOUS TUMORS AND TWO HUNDRED MELANIN TUMORS

DAVID T. SMITH, M.D.

Arch Surg. 1924;8(3):908-917.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The surgical pathologist is frequently confronted with the problem of making a differential diagnosis between xanthomatous tumors containing blood pigment and a true pigmented tumor of the melanin type. Xanthomatous tumors are always benign, although they may simulate sarcoma; while malignant melanin tumors are among the most fatal known to surgery. In some cases, the diagnosis is very easy, especially when we have the clinical history and examination; but in others it may be extraordinarily difficult.

When examined under the low power microscope, or even under the high dry, the sections from the two types of tumors may appear identical. We are not infrequently left in doubt even after obtaining the staining reaction for iron, because it is not uncommon to have hemorrhage in tumors of the melanin type. Neither can we always rely on the history and location of the tumor, because there are a number of xanthomatous tumors . . . [Full Text PDF of this Article]

Author Affiliations
BALTIMORE

From the Surgical Pathological Laboratory, Johns Hopkins Hospital.

Footnotes
This study was made on the same group of tumors that Dr. Charles A. Garrett reported in the preceding article.

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