This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (16)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

LAURENCE H. COFFIN, Jr., M.D.; JAY L. ANKENEY, M.D.

AMA Arch Surg. 1960;80(3):447-451.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

Acidosis has been observed to develop in both animals and humans while undergoing total cardiopulmonary by-pass.^1-4 The present study was designed to elucidate the etiology and type of acidosis encountered.

Procedure

Data were obtained during total body perfusions of 76 healthy, adult, mongrel dogs of average weight 18.9 kg. (range, 11.9-35.7). The animals were used without special preoperative preparation. Thiamylal (Surital, Parke-Davis) sodium, 12.5 mg. per kilogram of body weight, intravenously, was used to anesthetize both experimental and blood donor dogs. Ventilation was accomplished mechanically with intermittent positivepressure air and endotracheal intubation.

The right hemothorax was entered through the periosteal bed of the previously resected fifth rib. The superior vena cava was cannulated via the azygos vein and the inferior vena cava via the right atrial appendage with No. 22 polyvinyl catheters. The cavae were encircled with umbilical cord tape tourniquets. The superficial femoral artery was cannulated in . . . [Full Text PDF of this Article]

Author Affiliations
Cleveland

From the Department of Surgery, Western Reserve University School of Medicine, and University Hospitals of Cleveland.

Footnotes
Submitted for publication July 23, 1959.

Work supported by a grant from Cleveland Area Heart Society.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?