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Renal Blood Flow in Moderate Hypothermia
M. ONNIS, M.D.;
G. BOUNOUS, M.D.;
H. B. SHUMACKER, Jr., M.D.
AMA Arch Surg. 1960;80(4):593-596.
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Although there is general agreement that renal blood flow is depressed by body cooling, there is some disagreement concerning the extent of this alteration. These discrepancies may be related to the wide variation in the degree of hypothermia induced1,6,7,10,11,15 and, more particularly, to the methods for measuring renal blood flow.13 Some evidence has been presented in the literature indicating that the conventional clearance techniques for measuring renal plasma and blood flow are not necessarily reliable in the hypothermic animal. Harsing and his associates6 have pointed out that the clearance of para-aminohippurate may not be complete under hypothermic circumstances, possibly as a result of repression of secretory function of the tubules of the kidney. Balint and his colleagues2 have recently pointed out that this may also be true when the extraction rate is simultaneously determined.
Because of these discrepancies and the fact that we have been unable
. . . [Full Text PDF of this Article]
Author Affiliations
Indianapolis
From the Department of Surgery, Indiana University School of Medicine.
Footnotes
Submitted for publication Sept. 4, 1959.
Aided by grants from the Indiana Heart Foundation, the James Whitcomb Riley Memorial Association, and the U.S. Public Health Service, and by a contract between the Office of Naval Research, U.S. Navy, and Indiana University.
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