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  Vol. 80 No. 4, April 1960 TABLE OF CONTENTS
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Cancer Cells in the Blood Stream

LeROY LONG, M.D.; STUART ROBERTS, M.D.; RUTH McGRATH, B.S.; ELIZABETH McGREW, M.D.; WARREN H. COLE, M.D.

AMA Arch Surg. 1960;80(4):639-645.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Although reports of cancer cells in the blood stream have appeared sporadically in the medical literature over the past 100 years, only recently has it been possible with newer techniques to isolate and definitely identify these cells. This study is a continuation of work initially reported by Cole, Packard, and Southwick,1 in 1954. At that time cancer cells were isolated from fluid perfused through the major artery and collected from the major vein of colonic specimens containing carcinoma (Fig. 1). As a result of this work the study was amplified to include the examination of whole blood samples collected during the observation and treatment of patients with malignant disease. Such an approach has made it possible to study certain prognostic and therapeutic features, including response to surgery and chemotherapy.

Methods

Collection of Blood Samples.

—Peripheral blood samples are drawn from the antecubital vein. Blood samples from the veins draining . . . [Full Text PDF of this Article]


Author Affiliations

Chicago

From the Departments of Surgery and Pathology, University of Illinois College of Medicine, and the University of Illinois Research and Educational Hospitals.


Footnotes

Received for publication Sept. 24, 1959.

Aided by grants from American Cancer Society, Illinois Division, and U.S. Public Health Service (CS-9594).



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