This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (2)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Experimental Studies

JOHN W. SMITH, M.D.; JOHN E. CONNOLLY, M.D.

AMA Arch Surg. 1960;81(3):510-513.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The time limit of inflow occlusion for the purpose of direct-vision cardiac surgery has been studied in both euthermic^1-3 and hypothermic^4-8 dogs. Although some investigators have felt that anoxia of the heart is the most important factor in limiting the available time, it is now widely believed that the brain is more susceptible than the myocardium to anoxia.

During inflow occlusion, the brain is subjected not only to anoxia but also to a high venous pressure. In an attempt to determine whether the elevated venous pressure was responsible for augmenting the damaging effects of anoxia, the following studies were performed. The first compared the effect of simple decompression of the cerebral venous system during inflow occlusion with a control series without decompression. The second group of experiments studied the effect of pumping the cerebral venous blood into the arterial system during the period of inflow occlusion.

A. Simple . . . [Full Text PDF of this Article]

Author Affiliations
San Francisco

From the Surgical Research Laboratory, Stanford University School of Medicine.

Footnotes
Submitted for publication Nov. 30, 1959.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?