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JUN-ICHI SHIKATA, M.D.; A. W. KUNKLER, M.D.; HARRIS B SHUMACKER, Jr., M.D.; FRANKLIN D. NASH, M.D.; J. DONALD HUBBARD, M.D.

AMA Arch Surg. 1960;81(5):747-751.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Recent studies have yielded conclusive evidence that the denervated kidney of the dog has greater blood flow than the normally innervated kidney under the stress of anesthesia and especially under the stress of hemorrhagic hypovolemia.¹ The present study was undertaken to learn whether complete operative renal denervation would favorably influence the survival of animals after a period of renal ischemia. At the same time, we have investigated the possible influence of other methods which might alter the innervation of the kidney, as well as other measures known to increase renal blood flow.²

Materials and Methods

Adult mongrel dogs ranging in weight from 8 to 18 kg. were used. They were anesthetized by the intravenous administration of 5% thiopental sodium. Endotracheal intubation was carried out, and the lungs were rhythmically inflated with 100% oxygen by means of a mechanical respirator. Operations were performed with aseptic technique. The aorta was . . . [Full Text PDF of this Article]

Author Affiliations
Indianapolis

From the Department of Surgery and Pathology, Indiana University School of Medicine.

Footnotes
Submitted for publication April 19, 1960.

Aided by grants from the United States Public Health Service and the Indiana Heart Foundation.

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