This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (9)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

With Reference to Blood Lipid Levels in Rats on an Infarct-Producing Diet

W. STANLEY HARTROFT, M.D.; ROBERT M. O'NEAL, M.D.

AMA Arch Surg. 1961;82(1):69-73.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Myocardial infarction, usually the result of thrombosis of a coronary artery, has steadily increased in incidence over the last 30 years, so that at present it is a leading cause of death in this country. The traditional assumptions have been that coronary thrombosis was primarily a complication of underlying atheroma, that the increasing incidence of myocardial infarction was a result of increasing severity of atherosclerosis in our population, partially the result of increased age of the individuals, and that a decrease in the incidence of myocardial infarction would result only from prevention of atheroma.

Several developments have occurred that cast some doubt on these assumptions. First, evidence has been obtained that an increase in severity of atherosclerosis has not occurred in Great Britain in the last 40 years.¹ Second, there is the common observation that many patients with severe coronary atherosclerosis have no occlusive thrombosis and many with occlusive . . . [Full Text PDF of this Article]

Author Affiliations
ST. LOUIS

From the Department of Pathology, Washington University School of Medicine.

Footnotes
Submitted for publication June 16, 1960.

Supported by Research Grants No. H-4089 and No. H-1968 from the National Heart Institute, Institutes of Health, Bethesda, Md.

Presented at the Eighth Scientific Meeting of the International Cardiovascular Society, North American Chapter, Miami Beach, June 11, 1960.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?