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Effect on Cerebral Blood Flow of Normal Dogs

RICHARD T. SHACKELFORD, M.D.; STEPHEN A. HEGEDUS, M.D.

AMA Arch Surg. 1961;82(2):308-313.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The purposes of this paper are to compare the data obtained by a study of the cerebral blood flow of normal dogs measured by Kety's method before and at an average of six months after a bilateral superior cervical sympathetic ganglionectomy.

This work originated six years ago when one of us planned a carotid endarterectomy for arteriosclerotic occlusion and found the internal carotid artery occlusion was both extracranial and intracranial, preventing its removal. Convinced of the beneficial effect of lumbar sympathectomy in arterial occlusive disease of the lower extremities, the literature of the effect of superior cervical sympathetic ganglionectomy on the cerebral circulation was reviewed.

Literature of Subject

The experimental articles that seemed to us to be the most pertinent and significant were the following:

1. In 1858 Claude Bernard³ observed that in dogs a unilateral superior cervical sympathetic ganglionectomy caused an increase in the temperature of the brain . . . [Full Text PDF of this Article]

Author Affiliations
BALTIMORE

From the Surgical Research Laboratory, U.S. Veterans Hospital, Perry Point, Md.

Footnotes
Submitted for publication May 7, 1960.

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