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CHARLES A. ROSS, M.D.; GUNTHER E. KRAUS, D.V.S.

AMA Arch Surg. 1961;82(2):314-317.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The effect of tobacco tars on bronchial mucosa and the relationship of such products to bronchogenic cancer continue to be subjects of considerable interest and investigation. The increasing incidence of bronchogenic carcinoma and the statistical evidence showing a correlation with tobacco consumption demonstrate the need for continued work in this field. The studies here being reported will demonstrate a different technique for the evaluation of the effects of crude tobacco tar on regenerating tracheal epithelium as well as report the results obtained.

Methods and Materials

In this study a 2 cm. square area of the anterior lower cervical trachea was excised. Ivalon sponge, compressed to one-fourth its usual thickness, was substituted for the defect thus created. In 36 dogs, sterile, chemically clean Ivalon prostheses were substituted for a portion of the anterior wall of the trachea. These dogs were killed at intervals of 1, 2, 4, and 12 weeks to . . . [Full Text PDF of this Article]

Author Affiliations
BUFFALO

From the Departments of Surgery of the Roswell Park Memorial Institute and the University of Buffalo School of Medicine.

Footnotes
Submitted for publication May 9, 1960.

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