This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (3)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Tissue Reactions

AMOS R. KOONTZ, M.D.; ROBERT C. KIMBERLY, M.D

AMA Arch Surg. 1961;82(2):318-319.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Electron-Beam-Irradiated Ox Fascia

When ox fascia was introduced some years ago,^1,2 one of the great difficulties was its sterilization. It was impossible to remove it from animals in slaughter houses under aseptic conditions. Also it could not be heated without altering the collagen fibrils. It, therefore, had to be sterilized by chemical sterilization. It was found that an alcohol-acetone-aqueous solution of mercurochrome (Scott's solution) would do this satisfactorily. Laboratory tests showed that this solution would kill the spores of anthrax, tetanus, or gas bacillus in a comparatively short time. However, some quirk in the Federal law prevented the producers (Ethicon) from using this solution. It was then found difficult to find an adequate sterilizing solution which was not also irritant to the tissues, causing an unfavorable reaction when the material was implanted. Finally one was found which was fairly suitable, but even this solution had to be washed out . . . [Full Text PDF of this Article]

Author Affiliations
BALTIMORE

From the Department of Surgery of The Johns Hopkins University School of Medicine.

Footnotes
Submitted for publication March 18, 1960.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?