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HERBERT SOHN, M.D.; LESTER PERSKY, M.D.

AMA Arch Surg. 1961;82(5):719-722.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The problem of maintaining prolonged urinary drainage in patients with spinal-cord injuries has for many years taxed the best efforts of urologists and others interested in rehabilitation. Much has been written about the best forms of drainage, use of prophylactic antibacterials, diets, and fluids. Calculus formation, pyelonephritis, and sepsis, in general, all occur at a high incidence rate.¹ Sulfonamides have been extensively used in treating and preventing bladder infections since the advent of chemotherapy. Recently, long-acting sulfonamides have come into prominence in efforts to prevent the growth of urinary bacteria. One of these, sulfadimethoxine, which has been widely used for the treatment of upper respiratory infections,^2,7 is also useful in the treatment of soft-tissue⁸ and urologic infections.^7,11

Chemically, sulfadimethoxine* is 2,4-dimethoxy-6-sulfanilamido-1,3-diazine with the structural formula seen in the Figure. It is a colorless, odorless, tasteless, crystalline material which melts at 200 to 202 C. The drug . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

Formerly, Crile Veterans Administration Hospital, and now associated with the Strauss Surgical Group, Chicago (Dr. Sohn); Director, Department of Urology, University Hospitals, Cleveland, and Crile Veterans Administration Hospital, and Associate Professor of Urology, Western Reserve University, Cleveland, Ohio (Dr. Persky).

Footnotes
Received for publication Dec. 27, 1960.

This study was carried out under the auspices of the Crile Veterans Administration Hospital, Cleveland, Ohio.

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