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Effects of Incomplete Obstruction of the Common Bile Duct
T. MALCOLM ROBINSON, M.D.;
J. ENGLEBERT DUNPHY, M.D.
AMA Arch Surg. 1961;83(1):18-26.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Complete occlusion of the common bile duct causes changes in the standard liver function tests, which in general reflect accurately the severity of the lesion and the degree of hepatic damage which results; conversely, the return of these tests to normal indicates recovery from the lesion. In partial obstruction of the common duct this relationship between laboratory evaluation and actual degree of hepatic damage is by no means so clear-cut. With this in mind, the present study of partial common duct obstruction was undertaken. The goat was selected as the experimental animal, since its anatomic configuration permits obstruction of the common bile duct to be effected either above or below the entry of the pancreatic duct into the common duct.
Method
Operations were carried out under intravenous pentobarbital (Nembutal) anesthesia on female goats of mixed breed aged 6 to 12 months. After a preliminary laparotomy through a right subcostal incision
. . . [Full Text PDF of this Article]
Author Affiliations
PORTLAND, ORE.
From the Department of Surgery, University of Oregon Medical School.; Research Fellow in Surgery, University of Oregon Medical School, presently at St. George's Hospital, London (Dr. Robinson), and Professor and Chairman of the Department of Surgery, University of Oregon Medical School (Dr. Dunphy).
Footnotes
This paper was read at the 68th Annual Meeting of the Western Surgical Association, Detroit, Dec. 2, 1960.
This investigation was supported by a gift from the H. L. Berkman Foundation to the University of Oregon Medical School.
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