This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on Web of Science (2)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

HAROLD B. HALEY, M.D.; MARILYN C. McCARTHY, A.B.; MARTIN B. WILLIAMSON, Ph.D.

AMA Arch Surg. 1961;83(4):605-610.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The occasional recurrence of cancer in surgical incisions and anastomotic sites is well documented.^1-3 Investigations have been reported concerning methods of prevention of seeding of cancer cells into wounds during surgery and with local or systemic administration of various chemicals intended to destroy such cells.⁴ The thesis of this report is that the growth of cancer cells in a wound may be the result of 2 factors: (1) the presence of the cancer cells in the wound, and (2) metabolic interaction between the cancer cells and the wound which allows or stimulates growth of the cancer cells. Such interaction may stimulate or inhibit tumor growth. This thesis is based on observations made in the course of experiments in which transplantable human tumors have been injected into surgical incisions in rats. Two series of experiments are being reported. In the first, the effect of nutrition on tumor growth was . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

Stritch School of Medicine, Loyola University.; Associate Professor of Surgery (Dr. Haley), and Professor of Biochemistry (Dr. Williamson).

Footnotes
Aided by Grant No. T-120 from the American Cancer Society.

Presented at the 18th Annual Meeting of the Central Surgical Association, St. Louis, Feb. 18, 1961.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?