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ANTONIO DEMETZ, M.D.; LOUISE L. PHILIPS, Ph.D.; DAVID V. HABIF, M.D.; JULIUS H. JACOBSON, II, M.D.

AMA Arch Surg. 1961;83(6):883-886.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Replacement of venous segments remains one of the unsolved problems in vascular surgery. In most instances, the failure is due to thrombotic occlusion of the graft, with the thrombosis originating at the suture line.⁴

This project was carried out in order to determine the value of fibrinolysin in the prevention of thrombotic occlusion of the inferior vena cava. Venous autografts and various prosthetic materials were compared in both control and test groups because these represent extremes of success and failure in venous replacement.

Bryant² reports 8 of 10 successful venous autografts used for inferior vena caval replacement. He had no success when using freeze-dried arterial homografts, freeze-dried venous homografts, and a variety of prosthetic grafts. Egdahl⁵ reports no success with Orlon prostheses. Much work has been done on superior vena caval replacement. Results are conflicting,⁴ but, in general, fresh venous autografts are most successful, venous and . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK; BURLINGTON, VT.

From the Departments of Surgery, College of Physicians and Surgeons, Columbia University, New York, and the University of Vermont, College of Medicine.

Footnotes
Received for publication March 10, 1961.

This investigation was supported in part by a U.S. Public Health Service Research Grant H-1512-C6 and U.S. Public Health Service Research Grant H-5158 from the National Heart Institute.

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