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Surgical and Pathological Aspects

LT. COL. ARTHUR COHEN, MC; WILLIAM C. MANION, M.D.; FRANK C. SPENCER, M.D.; CAPT. STEPHEN W. CZARNECKI, MC; MICHAEL E. DeBAKEY, M.D.

AMA Arch Surg. 1962;84(6):628-642.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Among the earliest descriptions of occlusive disease at or near the origin of the major branches of the aortic arch were those by Savory in 1856¹⁸ and by Broadbent in 1875.² The various terms subsequently applied to this condition have included, "pulseless disease," "reversed coarctation," "aortic arch syndrome," "young female arteritis," and "chronic subclavian obstruction syndrome." Whatever the terminology used, all cases have been characterized by a decreased blood supply to the head, neck, and upper extremities, with the resultant signs and symptoms of ischemia of the affected parts.

The etiology of this condition remains unknown, although various causative factors, specific and nonspecific, have been considered.¹⁷ Pathologic findings in many reports would indicate atherosclerosis^3,7,8,14,21; however, others suggest that a nonspecific arteritis is the underlying cause.¹⁵ Some of the lack of agreement may arise from the fact that some reports have combined cases of isolated atherosclerotic . . . [Full Text PDF of this Article]

Author Affiliations
WASHINGTON; BALTIMORE; HOUSTON, TEXAS

Dr. Czarnecki's present address: Fitzsimmons General Hospital, Denver.; Dr. Cohen's present address: U.S. Army Hospital, Munich, APO 407, U.S. Forces.; From the Department of Surgery, Walter Reed General Hospital, Washington, D.C., and Cardiovascular Pathology Branch, Armed Forces Institute of Pathology, Washington 25, D.C.; Department of Surgery, The Johns Hopkins University School of Medicine and Hospital (Dr. Spencer); Department of Surgery, Baylor University School of Medicine (Dr. DeBakey).

Footnotes
Received for publication July 7, 1961.

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