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JOHN M. HARTZELL, M.D.; JOHN H. GRINDLAY, M.D.; JAMES T. PRIESTLEY, M.D.; JESSE L. BOLLMAN, M.D.

AMA Arch Surg. 1962;85(1):142-151.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

This experimental study on dogs was undertaken to measure the pH of duodenal contents before and after experimental procedures designed to prevent pancreatic secretions from entering the gastrointestinal tract. One procedure caused loss of all juice through an external fistula. Another caused atrophy of all acinar tissue. The third was total removal of the pancreas.

The question which this study attempted to answer was: Does it make any difference with regard to duodenal pH whether pancreatic juice is secreted but lost or not secreted at all?

Methods

We felt that the most physiologic way to measure differences, if any, after the 3 experimental surgical procedures was to make continuous in situ recordings of the pH of a localized region of the duodenum during fasting and then for 18 to 24 hours after feeding. The technique used was that of Humphreys and associates. A Mann-Bollman fistula was first established in each . . . [Full Text PDF of this Article]

Author Affiliations
ROCHESTER, MINN.

Fellow in Surgery (Dr. Hartzell); Section of Surgical Research (Dr. Grindlay); Section of Surgery (Dr. Priestly), and Emeritus Member, Section of Biochemistry (Dr. Bollman). Mayo Clinic and Mayo Foundation, Rochester, Minnesota.

Footnotes
Read at the 69th Annual Session of the Western Surgical Association, San Francisco, Nov. 30, 1961.

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