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Experimental and Clinical Studies

HIROSHI MIYAKE, M.D.; TAKEHARU HISATSUGU, M.D.

AMA Arch Surg. 1962;85(3):442-455.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Generally speaking, intrahepatic and postoperative residual gallstones are regarded as not being amenable to surgical therapy. Pribram,¹ Walters and Wesson,² and Best and co-workers³ employed various organic solvents, such as ethyl ether or chloroform, agents which are, however, aimed at dissolution of cholesterol stones. Bilirubin stones, and bilirubin-calcium stones in particular, are scarcely soluble in such organic preparations, and hence arises the question of the toxicity and pharmacologic side-effects of such measures. Although the incidence of cholesterol calculosis is increasing in Japan of late, bilirubin-calcium calculosis is characteristic of this type of involvement in Japan, and its incidence exceeds that of the former⁴ in this locality. Intrahepatic stones, residual gallstones, and most stones of the common bile duct are classified as bilirubin-calcium stones in Japan, and adequate therapy for them is urgently needed.^5-7

Chemical Studies

One of us (T. H.)⁸ introduced rheologic methods for . . . [Full Text PDF of this Article]

Author Affiliations
FUKUOKA, JAPAN

Professor of Surgery, First Department of Surgery (Dr. Miyake), Postgraduate Student, Faculty of Medicine (Dr. Hisatsugu), Kyushu University.

Footnotes
Received for publication Nov. 13, 1961.

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