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A Controlled Study of Antibiotic Prophylaxis

HEONIR ROCHA, M.D.

AMA Arch Surg. 1962;85(3):456-459.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

There have been several recent reports condemning the unnecessary prophylactic use of antibiotics in the majority of surgical operations, particularly in the so-called clean cases.^1-4 They have shown that these drugs do not prevent postoperative infections and that the incidence of antibiotic-resistant strains of bacteria increases.^2,4 However, 2 aspects pertaining to this subject deserve further consideration. (1) The incidence of infection after a surgical procedure varies a great deal from one hospital to another.^5-9 (2) The bacterial strains commonly found in a hospital environment might differ from one hospital to another. These facts explain, at least in part, the variability of incidence and severity of hospital-acquired infections found in different reports.

Therefore, it seemed important both to observe the rate of wound infection in a general hospital such as in Salvador, Bahia (Brazil), and to perform a controlled clinical study on the effect of the prophylactic use . . . [Full Text PDF of this Article]

Author Affiliations
BAHIA, BRAZIL

Assistant Professor, Department of Medicine, Hospital das Clínicas, University of Bahia.

Footnotes
Submitted Aug. 24, 1961.

This work is part of a thesis presented to the University of Bahia School of Medicine.

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