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II. Acute Ligation of the Left Circumflex Coronary Artery With and Without Hypothermia

CHARLES FINEBERG, M.D.; NICHOLAS FORIS, M.D.; RUDOLPH C. CAMISHION, M.D.

AMA Arch Surg. 1962;85(5):717-719.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Moderate hypothermia of 30 C in dogs has been shown to diminish oxygen consumption by approximately 50%.¹ In addition, we have demonstrated that after division of the circumflex coronary artery in normothermic dogs, perfusion of the distal vessel with only 10 ml. per minute of oxygenated blood will maintain the heart in a normal sinus rhythm.³ Thus, one might expect that after ligation of this artery moderate hypothermia would increase the survival rate of these animals.

Haeger⁵ in 1959 ligated an unspecified coronary artery in 3 groups of dogs. In the first group, the artery was ligated in normothermic animals with a resultant 94% survival rate. The second group of dogs were made hypothermic. Ligation of the artery in these animals was followed by a 65% survival. The third group consisted of hypothermic dogs whose hearts were arrested with acetylcholine. Ninty-six per cent of these survived ligation . . . [Full Text PDF of this Article]

Author Affiliations
PHILADELPHIA

From the Department of Surgery, The Jefferson Medical College of Philadelphia.

Footnotes
Received for publication April 20, 1962.

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