This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (10)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

GEORGE R. DAICOFF, M.D.; ROGER HARMON, M.D.; JOHN VAN PROHASKA, M.D.

AMA Arch Surg. 1962;85(5):800-807.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In May, 1951, Dr. Charles Huggins performed the first bilateral adrenalectomy for far-advanced carcinoma of the breast.² To-day, this decisive step represents a fruitful, clinical application of basic knowledge established by the experiments conducted by Dr. Huggins.^3,4 These experiments and the results of their clinical applications confirm the existence of hormonal influence on cancer of the breast and cancer of the prostate gland.¹ The combined national effort currently directed toward the search for chemotherapeutic agents has not matched the achievements obtained by the clinical application of one man's research. This is evident in the comparison of the nature and the extent of the response induced by endocrine ablation to the current standard of favorable response induced by various anticancer drugs.

Despite reports of its palliative effects and relatively uncomplicated surgical course, adrenalectomy has not been adequately emphasized as an effective therapy of inoperable cancer of the breast . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Department of Surgery of the University of Chicago.

Footnotes
Presented at the 19th Annual Meeting of the Central Surgical Association, Cincinnati, Feb. 21-24, 1962.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?