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Response to Occlusion of the Portal VeinBlood Pressure and Renal Blood Flow
MARIO ONNIS, M.D.;
HARRIS B. SHUMACKER, JR., M.D.;
GUSTAVO BOUNOUS, M.D.
AMA Arch Surg. 1962;85(6):897-900.
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The present study was undertaken in order to investigate arterial blood pressure and renal blood flow responses to acute temporary occlusion of the portal vein and to compare them with those occurring with occlusion of the superior mesenteric vein and with occlusion of these 2 veins when combined with prior clamping of various visceral arteries.
Materials and Methods
Adult healthy dogs ranging in weight from 11.2 to 17 kg. were used. They were anesthetized by the intravenous injection of 5% thiopental sodium. Tracheal intubation was carried out, and adequate ventilation was maintained by administration of oxygen through a mechanical respirator. The vessels to be occluded were dissected free. The mean arterial blood pressure was determined by means of a U-tube mercury manometer connected with a plastic catheter inserted into the aorta through a femoral artery. Renal blood flow was determined by a direct method which has been described previously.1 Renal
. . . [Full Text PDF of this Article]
Author Affiliations
INDIANAPOLIS
From the Department of Surgery and the Heart Research Center, Indiana University School of Medicine.
Footnotes
Submitted for publication Feb. 15, 1962.
Aided by grants from the James Whitcomb Riley Memorial Association, by Public Health Service research grant (H-203 C5) from the National Heart Institute, National Institutes of Health, Public Health Service, and by the Indiana Heart Association.
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