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CALLISTO DANESE, M.D.; ROBERT DIAZ, M.D.; JOHN M. HOWARD, M.D.

AMA Arch Surg. 1963;86(1):5-12.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The regional edema that often follows the onset of acute thrombophlebitis of an extremity is the expression of inadequate fluid drainage, and it would appear that the occlusion of the inflamed veins by thrombi is a major factor in the causation of the edema.

Several investigators have demonstrated that the surgical occlusion by ligature of the major veins draining a limb does not always result in the formation of edema, and that when edema occurs, it is often minimal and of short duration (Ranvier, Roger, Leriche, Young, and others).^1,2

It has also been demonstrated that when the major venous channels of a limb are occluded, much of the drainage from the limb is taken over by the lymphatic system. Emminghaus in 1889 demonstrated that inflation of a cuff at the base of a limb, obstructing the venous return, resulted in a marked increase in the lymph drainage from the . . . [Full Text PDF of this Article]

Author Affiliations
PHILADELPHIA

Presently at Mt. Sinai Hospital of Cleveland, Ohio (Dr. Danese).; From The Department of Surgery, Hahnemann Medical College.

Footnotes
Read before the 10th Scientific Meeting of the International Cardiovascular Society, North American Chapter, Chicago, June 23, 1962.

This study has been supported by grants from the American Heart Association and from the National Heart Institute.

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