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Osteogenic Sarcoma in a Luminous Watch Dial Painter
CARL DAVIS, JR., M.D.;
R. GORDON BROWN, M.D.;
R. W. ALEXANDER, M.D.
AMA Arch Surg. 1963;86(2):190-195.
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After the isolation and identification of radium by the Curies, radium and other closely related radioactive elements were utilized in the treatment of a number of medical disorders, particularly gout,1 arthritis,2,3 syphilis,4 hypertension,5 epilepsy, multiple sclerosis,6 leukemia,7 and various types of anemia.8-10 The oral and intravenous use of radium was well established not only in this country, but also abroad. Although the toxic manifestations of radium and its associated elements were not well defined at that time, there was, nonetheless, much enthusiasm for this mode of therapy because of the presumed clinical improvement in a large number of cases. Looney et al.11 recently emphasized that toxic effects were not anticipated to develop 10 to 20 years after the use of radium therapy. It has been stated that the administration of soluble radium salts has continued, at intervals, until the present time in
. . . [Full Text PDF of this Article]
Author Affiliations
CHICAGO
From the Departments of Surgery (Dr. Davis), Medicine (Dr. Brown), and Pathology (Dr. Alexander), Presbyterian-St. Luke's Hospital and The University of Illinois College of Medicine.
Footnotes
Submitted for publication March 21, 1962.
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