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Tumor Arising in an Area of Radiation Injury

R. W. BRENNER, M.D.; R. GARRET, M.D.

AMA Arch Surg. 1963;86(3):471-476.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

This is a case report of a patient with chondrosarcoma-like tumor of the soft tissues developing in an area of radiation dermatitis five years after external cobalt⁶⁰ radiotherapy for bronchogenic carcinoma. A similar case diagnosed as osteogenic sarcoma was reported in 1951.³ Recently, lesions histologically resembling those in the case to be presented were reported as sarcoma-like tumors.²³

Extraskeletal chondrosarcomas are very rare. The first case reports appeared in the literature in 1943³³ and 1953.²⁷ Other cases have been reported recently.^28,30 Upon the discovery of x-rays in 1895, soft tissue sarcomas following local irradiation were noted as early as 1904.²⁰ In 1909 Coenen stated (cited by Jones¹⁴) that 12% of tumors after x-ray treatment were sarcomas. Most authors since then have indicated that squamous cell carcinoma is the main tumor developing after local external radiation.^{4,5,7,15,31,32} Conversely, sarcomas have been found usually . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

Resident in the Department of Surgery (Dr. Brenner); Director, Department of Pathology (Dr. Garret).

Footnotes
Submitted for publication Oct. 22, 1962.

The Roosevelt Hospital, New York.

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