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Effects on Vascular Responses in the Lower Extremity of Patients With Arteriosclerosis Obliterans

DAVID A. TICE, MD; GEORGE E. REED, MD; EDWARD J. MESSINA, BS; EMMETT CLEMENTE, MS; WALTER REDISCH, MD

AMA Arch Surg. 1963;87(3):461-463.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

Reports on the clinical results of lumbar sympathectomy have varied from great satisfaction to the denial of any essential benefit.^1,2 Clinical evaluation of therapeutic results in chronic disease is notoriously difficult.³ On the other hand, it must be admitted that a rationale established on purely experimental basis may not necessarily always be borne out by clinical experience. Nevertheless, if reliable methods to ascertain the physiologic effects of a procedure are available, it is preferable to establish such on an objective basis rather than to rely on clinical impressions.

With this in mind the effects of lumbar sympathectomy upon blood flow to skin and muscles of the lower extremity in patients with arteriosclerosis obliterans were measured plethysmographically.

Methods and Material

Presympathectomy measurements of blood flow were made on 12 limbs in eight patients with non-gangrenous obliterative atherosclerosis. In six, unilateral sympathectomy was performed and post-sympathectomy data (two to . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Cardiovascular Unit of The New York University Medical Center, Departments of Surgery and Medicine of New York University School of Medicine, and the New York University Research Service, Goldwater Memorial Hospital.

Footnotes
Submitted for publication Jan 16, 1963.

This work was supported in part by the United States Public Health Service under grant No. HE-03097-06 and in part by the Health Research Council of The City of New York under contract No. U-1089.

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