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A Revised Technique Based on Anatomic Considerations

BERNARD SIGEL, MD

AMA Arch Surg. 1963;87(5):788-791.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Partial hepatectomy has served as a valuable experimental tool with which to study liver regeneration and function. The presence of rather complete fissures between the hepatic lobes of laboratory animals has greatly facilitated resection and has provided a means of estimating the amount of tissue which has been removed. The techniques of partial excision in the rat² and the dog¹ are well standardized. Both methods are designed to resect about two-thirds of the liver and consist of ligating the base of the lobes to be removed with amputation of liver tissue distal to the ligature. Although this procedure is simple and rapid, it is associated with a high mortality where other surgical maneuvers are needed concomitantly (eg, partial hepatectomy and Eck fistula in dogs). This situation could be due to 1) excessive trauma of operation associated with retention of devitalized liver tissue, 2) production of a severe physiologic . . . [Full Text PDF of this Article]

Author Affiliations
PHILADELPHIA

From the Department of Surgery, Woman's Medical College of Pennsylvania.

Footnotes
Submitted for publication April 16, 1963.

Recipient of Research Career Development Award from the National Institute of Arthritis and Metabolic Diseases, Public Health Service, No. AM-K3-16,679; Assistant Professor of Surgery, Woman's Medical College of Pennsylvania.

Supported by Research grant No. A-4255-C1 from the National Institute of Arthritis and Metabolic Diseases, Public Health Service.

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