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Effects on Pulmonary Blood Flow

KHLAR E. McDONALD, MD; CAPT FRANK A. CAMP, USAF (MC); WORTHINGTON G. SCHENK, JR., MD

AMA Arch Surg. 1963;87(5):796-800.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The effect of mechanical ventilation on pulmonary blood flow has both experimental and clinical implications. Most major surgical procedures are currently being done while using mechanical ventilation. Experimental plans often require thoracotomy and, hence, mechanical ventilation.

This study was aimed at evaluating alterations in pulmonary blood flow resulting from ventilation with three commonly used mechanical ventilators.

Methods

Eleven mongrel dogs weighing from 10.9 to 21.31 kg were studied under light intravenous sodium pentobarbital (12 mg/kg) anesthesia. Each animal was intubated with a cuffed endotracheal tube, and mechanical ventilation with room air was accomlished by one of three ventilators: a) intermittent positive-negative piston type (Jefferson*), b) continuous positive pressure operated diaphragm (pneophore), or c) positive-negative pressure operated diaphragm (anesthetizer-vaporizer-resuscitator, [A-V-R] ). Polyethylene catheters of identical dimensions were placed in a peripheral artery, the pulmonary artery, and the left atrial appendage. From these, arterial pressure and pulmonary artery less atrial differential pressure . . . [Full Text PDF of this Article]

Author Affiliations
BUFFALO

Buswell Fellow in Surgical Research (Dr. Schenk).; From the Department of Surgery, School of Medicine of the State University of New York at Buffalo and the Edward J. Meyer Memorial Hospital.

Footnotes
Submitted for publication April 15, 1963.

Supported by grants-in-aid from the United States Public Health Service H-3181 and the Heart Association of Erie County.

The contents reflect the opinions of the author and are not to be construed as official Air Force Policy.

Animals used in these experiments were treated in accordance with the rules regarding animal care established by the American Medical Association.

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