This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (7)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

ROBERT A. HARDIN, MD; HARRIS B. SHUMACKER, JR., MD; CHIEN SHENG SU, MD

AMA Arch Surg. 1963;87(5):831-835.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Oxygen saturation of the portal venous blood has been found to be higher than that of the systemic venous blood of anesthetized and unanesthetized dogs^1,2 and human subjects.^2-4 This has been observed in patients with and without liver disease. Regardless of the role of arteriovenous shunting in bringing about an elevated portal venous oxygen saturation, a number of other factors might conceivably have a part. This study was initiated in order to investigate several of them. It was our aim to learn the effect of the anesthetic state, of active body exercise, of digestion, and of hypoxia.

Materials and Methods

Adult mongrel dogs weighing from 11 to 18 kg were used. Anesthesia was induced by the intravenous administration of sodium thiopental. Tracheal intubation was carried out, and the lungs were inflated rhythmically with 100% oxygen by means of a mechanical respirator. The animals had received nothing by mouth . . . [Full Text PDF of this Article]

Author Affiliations
INDIANAPOLIS

From the Department of Surgery and the Heart Research Center, Indiana University School of Medicine.

Footnotes
Submitted for publication May 7, 1963.

This investigation was supported in part by Public Health Research grant H-207 from the National Institutes of Health and in part by a grant from the James Whitcomb Riley Memorial Association.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?