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HERMAN T. BLUMENTHAL, MD; J. G. PROBSTEIN, MD; A. W. BERNS, BS

AMA Arch Surg. 1963;87(5):844-850.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Several types of relationships between pancreatitis and diabetes mellitus have been studied: (1) A transitory hyperglycemia and glycosuria have been observed during acute attacks of pancreatitis which have been attributed to secondary, temporary effects of the acute inflammatory process on the islets of Langerhans. After recovery from the acute episode, the defect in carbohydrate metabolism usually disappears.¹ However, the damage appears to be permanent in some cases since Shumacker² has reported that 3%-10% of patients with acute pancreatitis develop permanent diabetes. (2) The development of acidosis and coma during an attack of acute pancreatitis in an already established diabetes has been particularly stressed by Root³ and more recently by Hughes.⁴ It appears that in such cases the diabetes antedates the onset of acute pancreatitis. But it remains uncertain whether or not the presence of diabetic coma renders the patient more susceptible to attacks of acute pancreatitis. . . . [Full Text PDF of this Article]

Author Affiliations
ST. LOUIS

From the Laboratories of the Clinical Research Program on Aging, Veterans Hospital, Jefferson Barracks, and the Departments of Surgery, The Jewish Hospital and Washington University of Medicine.

Footnotes
Submitted for publication May 22, 1963.

This study was supported in part by the Louis Monheimer-Clara K. London Memorial Research Fund and in part by Grant No. AM-07116, National Institute of Arthritis and Metabolic Disease, National Institutes of Health.

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