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RICHARD V. FIDDIAN, M Chir, FRCS; DAVID BYAR, AB; EDWARD A. EDWARDS, MD

AMA Arch Surg. 1964;88(1):83-90.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

The literature on the subject of the effect on blood flow of vessel stenosis reveals results and conclusions ranging widely from Shipley and Gregg's⁵ statement that they found no justification for the contention that a rather marked degree of external constriction is required to produce a significant reduction in flow through a vessel, to the demonstration by Cannon et al¹ that a 99.1% reduction in lumen area produced a mere 30% fall in flow. May, DeWeese, and Rob⁴ have summarized work in this field and find that with a 1-cm-long stenosis the luminal area in the canine iliac artery required reduction to 20% of normal to begin to decrease blood flow.

The variation in results previously reported may be due to many factors, such as failure to monitor viscosity changes in the dog's blood, inadequate control or record of pressures (Mann et al³), unreliable flow . . . [Full Text PDF of this Article]

Author Affiliations
BOSTON

In receipt of a Peel Medical Trust Traveling Fellowship (Dr. Fiddian).; From the Departments of Surgery and Anatomy, Harvard Medical School and Peter Bent Brigham Hospital.

Footnotes
Read before the 11th Scientific Meeting of the International Cardiovascular Society, North American Chapter, Atlantic City, NJ, June 15, 1963.

Aided by grants from the Medical Foundation, Inc., the American Heart Association, and the Milton Fund of Harvard University.

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