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Oxygen Tension Monitoring During Clinical Anesthesia
NICHOLAS M. GREENE, MD;
MAUREEN H. BULL, MD
AMA Arch Surg. 1964;88(2):225-228.
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Molecular oxygen in adequate amounts is a basic prerequisite for normal tissue metabolism and function. The amount of molecular oxygen in tissue, or tissue oxygen tension, is, however, determined by a large number of different factors (Table). In a state as complex as clinical anesthesia, the majority if not all of these factors may simultaneously be altered and often may be altered in different directions. During clinical anesthesia not only may alveolar ventilation and oxygen tension in the inspired air be altered, but cardiac output, peripheral vasomotor tone, and tissue oxygen consumption may also simultaneously be changed. It becomes impossible to anticipate what effect, if any, a particular anesthetic agent or technique will have on tissue oxygen tension. It is likewise impossible to evaluate under clinical conditions whether tissue oxygenation is normal. Blood pressure, pulse, respiration, and color are inadequate for this purpose except under extreme conditions. A normal or
. . . [Full Text PDF of this Article]
Author Affiliations
NEW HAVEN, CONN
From the Division of Anesthesiology, Yale University School of Medicine, and the Department of Anesthesia, Grace-New Haven Community Hospital.
Footnotes
Received for publication Sept 16, 1963.
Read before the Section on Anesthesiology, Annual Meeting, AMA, June, 1963.
Supported by research grant HE 03359-05, National Institutes of Health, United States Public Health Service.
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