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L. R. DRAGSTEDT, II, MD; L. J. LAWSON, MD

AMA Arch Surg. 1964;88(2):287-289.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

A significant advance in evaluation of gastric function occurred in 1943 when the quantitative measurement of the fasting gastric secretion of acid was first applied clinically.² In the first papers fasting gastric hypersecretion was realized to be the major factor in the genesis of duodenal ulcer. Gastric output was measured by recording the volume aspirated from the stomach over a known (12-hour) length of time. The concentration of acid in this aspirate was then determined and expressed as Free Acidity in clinical units. One clinical unit was that amount of acid neutralized by 1 cc 0.1 N NaOH.

Later gastric output was described in milligrams,⁶ millimols,¹ and finally milliequivalents.³ Total gastric output of acid is now commonly expressed in terms of milliequivalents, and over a period of years a set of normal values for various conditions has been determined.⁴ These are for the 12-hour . . . [Full Text PDF of this Article]

Author Affiliations
DES MOINES, IOWA

From The Department of Surgery and Surgical Research, Veterans Administration Hospital.

Footnotes
Received for publication Sept 30, 1963.

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