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ARNOLD G. DIETHELM, MD; MARVIN H. SLEISENGER, MD; WILLIAM F. NICKEL, JR., MD

AMA Arch Surg. 1964;88(3):389-396.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

I. Introduction

Acute fulminating ulcerative colitis may develop spontaneously in apparently healthy individuals, or it may occur in patients with known chronic ulcerative colitis. The disease may progress rapidly and reach its peak in two to three weeks or continue for weeks or months with exacerbations and remissions. Certain cases, however, are irreversible with current medical management and terminate either in perforation of the colon or in a syndrome known as "toxic megacolon" (Fig 1).⁷ This is characterized by abdominal distention, fever, diarrhea, and pain, and will frequently progress to perforation of the colon.⁵ Careful, intensive medical management will control the disease in some individuals, but it is impossible to predict success or failure.⁶ These patients present difficult problems and frequently require primary colectomy. The purpose of this paper is to present our experience with 14 patients with acute fulminating ulcerative colitis who were treated by primary . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Departments of Surgery and Medicine, The New York Hospital-Cornell Medical Center.

Footnotes
Submitted for publication Oct 29, 1963.

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