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R. A. L. MACBETH, MD, FACS, FRCS(C); J. G. BEKESI, BSc

AMA Arch Surg. 1964;88(4):633-637.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In spite of the fact that plasma glycoproteins have recently been the subject of intense interest and investigation by clinically orientated biochemists,^10,11,13,14 knowledge of this ever expanding field has, as yet, received scant mention in clinical publications.

The presence of free carbohydrate in the blood, largely in the form of glucose, has been recognized for years. However, an appreciation of the fact that hydrolysis of plasma protein releases additional reducing substances is of relatively recent origin,⁶ and the isolation and identification of these protein-bound sugars has been completed only in the last few years.^1,2,7,8 Such conjugated protein-carbohydrate complexes, when occurring in the plasma, are referred to as plasma glycoproteins.

Six monosaccharides have been isolated and identified as forming the carbohydrate of the plasma glycoproteins.¹² These include galactose and mannose (the hexoses), glucosamine and galactosamine (which occur as N-acetyl derivatives and are collectively referred to as the . . . [Full Text PDF of this Article]

Author Affiliations
EDMONTON, ALTA, CANADA

Department of Surgery and the Surgical-Medical Research Institute, University of Alberta.

Footnotes
Read before the 71st Annual Session of the Western Surgical Association, Galveston, Tex, Nov 21-23, 1963.

These investigations were supported by grants from the National Cancer Institute of Canada (NCI No. 226).

The methodology utilized in these studies has not been detailed but is included in previous papers by us to which reference is given. Also no attempt has been made to include a bibliography of the literature dealing with this rapidly expanding field. The papers of Spiro, Stary, or Winzler should be consulted in this regard.

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