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Untreated, Low-Pressure Ventricular Septal DefectRepeated Cardiac Catheterization
J. G. MUDD, MD;
Y. AYKENT, MD;
L. FAGAN, MD;
J. B. SHIELDS, MD;
M. DAVIS, MD;
J. DONAHOE, MD;
C. R. HANLON, MD
AMA Arch Surg. 1964;89(1):126-130.
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The choice of treatment in ventricular septal defect is based on observation of the natural history of this entity. A number of authors * have reported the progress of untreated patients with isolated ventricular septal defect, indicating a spectrum of possibilities varying from spontaneous closure to progression of pulmonary hypertension.
We are reporting our studies of ventricular septal defect in 32 children below the age of 12 years at the time of initial observation. Most of them were asymptomatic with pulmonary arterial systolic pressure below 30 mm Hg. Catheterization and cineangiography were repeated from one to seven years after the initial studies. In two instances, a third set of observations followed the second by three to five years.
Method
Right heart catheterization was performed in the usual way, by venous cutdown or by percutaneous venipuncture in the groin. Pressures and intracardiac oxygen saturations were obtained from various chambers and cineangiograms in
. . . [Full Text PDF of this Article]
Author Affiliations
ST. LOUIS
Research Fellow, St. Louis Heart Association (Dr. Aykent), Trainee in Cardiovascular Surgery (Dr. Shields).; From the departments of internal medicine, pediatrics, and surgery and the Center for Cardiovascular Research, St. Louis University.
Footnotes
Read before the 21st Annual Meeting of the Central Surgical Association, Rochester, Minn, Feb 27-29, 1964.
Aided by grants HE-06312 and HE-5299-06, United States Public Health Service, and by the John A. Hartford Foundation.
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