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Effect of Immunosuppressive Drugs

BERNARD FISHER, MD; SUN LEE, MD; EDWIN R. FISHER, MD; AKIYOSHI SAKAI, MD; MARVIN RABINOVITZ, BS

AMA Arch Surg. 1964;89(1):65-87.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Ever since Schiff (1884)¹ inserted homologous thyroid glands into the peritoneal cavity of dogs, several generations of laboratory investigators and surgeons have reported their findings following implantation of this gland. It has been placed as a free graft into the subcutaneous tissue and abdominal musculature of guinea pigs,^2-4 the anterior chamber of the guinea pig,⁴ adult dog and rabbit eye,⁵ into different parts of the body of rabbits of various ages,⁶ rats,^4,7-10 cats,¹¹ and dogs,^12,13 all under a variety of experimental conditions. In recent years implantation using the Millipore chamber technique has received attention.^14-16 The human, subsequent to Kocher's first implantations (1908)¹⁷ in patients with thyroid deficiency, has also been a repeated recipient.^18-23

Generated by clinical urgency, homografting of the parathyroid has perhaps received even more attention. In the laboratory the observations of Camus (1905)²⁴ in the rabbit, . . . [Full Text PDF of this Article]

Author Affiliations
PITTSBURGH

From the Department of Surgery, Laboratory of Surgical Research, and the Department of Pathology, University of Pittsburgh School of Medicine.

Footnotes
Read before the 21st Annual Meeting of the Central Surgical Association, Rochester, Minn, Feb 27-29, 1964.

Supported by United States Public Health Service grant No. CA-03731 and the Pennsylvania Heart Association, Inc.

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