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RICHARD A. FREIBERG, MD; ROBERT D. RAY, MD

AMA Arch Surg. 1964;89(3):417-427.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

While it is generally accepted that living autogenous bone is the most effective bone grafting material available,^1-6 the relative value of various substitutes remains controversial. Homogenous and heterogenous bone, ivory,⁷ cow horn,⁷ and inorganic salts such as calcium phosphate^8-10 and sulphate¹¹ have all been studied as well as bone modified in many ways including boiling,^2,12,13,10 freezing,^2,8,14,15 lyophilizing,^15,16 deproteinizing,^{17, 14,5} and decalcifying.^14,17-19 F. J. Marchand as early as the 19th century stated:

It is already sufficiently known that either fresh bone taken from living animals or bone killed in various ways can serve as a more or less complete substitute for and cause healing of a bone defect.²⁰ However, it still remains to be determined which of the various types of devitalized bone may serve best in facilitating healing of a skeletal defect. The following study was carried out . . . [Full Text PDF of this Article]

Author Affiliations
CINCINNATI; CHICAGO

From the Department of Orthopaedic Surgery, Presbyterian-St. Luke's Hospital and the University of Illinois Research and Educational Hospitals.

Footnotes
Read before the Annual Meeting of the American Orthopaedic Association, Bermuda, May 30, 1962.

This work was supported by the National Institute of Health grant At(11-1)-507 and the Samuel Higby Camp Foundation.

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