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  Vol. 89 No. 3, September 1964 TABLE OF CONTENTS
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Immunologic Response To Autologous Cancer Vaccine

MUHAMMAD ASWAQ, MD; VICTOR RICHARDS, MD; SHEILA McFADDEN

AMA Arch Surg. 1964;89(3):485-487.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In the past few years the immunology of cancer has been the subject of feverish activity and great promise. The long anticipated hope that cancer vaccine will some day rid humanity of the scourge of cancer is just beginning to materialize. Numerous reviews1-8 on the immunologic aspects of cancer have adequately summarized the accomplishments of many scientists in this field. The purpose of this paper is twofold: first, to report our experiences with autogenous cancer vaccine in terminal cancer patients, and second, to show by passive cutaneous anaphylaxis in guinea pigs the ability of cancer patients to produce humoral antibodies to autologous tumor.

Twenty-one patients formed the subject of this study. All had inoperable cancer with unfavorable prognosis. The tissue for the autogenous vaccine was obtained aseptically at the time of surgery and stored at —4 C. The whole tumor homogenate was prepared by cutting 1 gm of tumor . . . [Full Text PDF of this Article]


Author Affiliations

SAN FRANCISCO

From the Surgical Research Laboratories Presbyterian Medical Center.


Footnotes

Submitted for publication March 12, 1964.

This work was supported by a grant from the Damon Runyon Memorial Fund for Cancer Research, Inc.



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