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High Speed Cinematograph Studies

TED P. BOND, MD; JOHN R. DERRICK, MD; M. MASON GUEST, MD

AMA Arch Surg. 1964;89(5):887-890.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Intravascular aggregation of red blood cells has been described in a number of infectious conditions and injuries. Knisely¹ has recently published an excellent review. Bigelow and associates² demonstrated intravascular aggregation occurring in surface cooled animals. They observed this phenomenon to occur at about 32 C becoming severe at 25 C to 20 C. Recently, it has been suggested that the aggregation these workers observed was due to the decrease in arterial pressure, which accompanies surface cooled animals, rather than the hypothermia per se.³

This report describes the microcirculation before and during profound hypothermia in which the blood pressure and perfusion rate were maintained relatively constant.

Methods

Observation and recording of the behavior of the red blood cell in the microcirculation were made possible through the use of high-speed cinephotography. The mesenteries of dogs, anesthetized with pentobarbitol, were mounted vertically on a movable stage. A 1,500 watt General . . . [Full Text PDF of this Article]

Author Affiliations
GALVESTON, TEX

From the departments of Physiology and Surgery, University of Texas Medical Center.

Footnotes
Read before the 12th Scientific Meeting of the International Cardiovascular Society, North American Chapter, San Francisco, June 20, 1964.

Supported in part by USPHS grants HE-06238-04 and HE-03717-06.

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