 |
|
Rare Nonkeratinizing Malignancies of Anal RegionPathologic Features
LEWIS GRODSKY, MD
AMA Arch Surg. 1965;90(2):216-221.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
|
|
|
THE malignancies of the anal canal, which comprise less than 5% of the malignancies involving the colon and rectum, are almost always keratinizing squamous cell epidermoid cancers. The squamous cell lesions are distinguished by epithelial pearl keratin formations. However, occasionally a nonkeratinizing cancer appears in the anal canal or perianal region and, because of its rarity, it is often overlooked in differential diagnosis. The various tumors arise from specific zones of origin in the anal canal.
Five types of nonkeratininizing cancers have been seen in the anal region. These nonkeratinizing anal malignancies show wide variations in cellular pattern and in dynamics of growth. Two of them, the basal cell carcinoma and perianal Bowen's disease, have a low invasive potential and, if recognized early, can easily be eradicated by local excision. The malignant melanoma of the anal canal, however, offers an almost hopeless prognosis even after the most radical surgery. The
. . . [Full Text PDF of this Article]
Author Affiliations
SAN FRANCISCO
From the Department of Surgery (Proctology), University of California School of Medicine.
Footnotes
Submitted for publication Aug 10, 1964.
Read before the Section on Proctology at the 113th Annual Meeting of the American Medical Association, San Francisco, June 21-25, 1964.
Reprint requests to 2211 Post St, San Francisco, Calif 94115.
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
|
