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An Experimental Study

THOMAS BAITZ, MD; GEORGE A. HALLENBECK, MD; ROY G. SHORTER, MD; GERALD W. SCOTT, MD; CHARLES A. OWEN, JR., MD; JAMES C. HUNT, MD

AMA Arch Surg. 1965;91(2):276-287.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IN THE course of clinical renal transplantation, a period of renal ischemia is inevitable. When living donors are used, the time the kidney is without blood flow can be kept short enough that damage from ischemia is minimal. Use of cadaveric kidneys introduces longer and more variable periods of renal ischemia and makes damage to the kidneys from this cause a more serious problem. The solution to the problem requires, first, that kidneys be obtained in the best possible condition and, second, that once the kidneys are removed, further deterioration be slowed as much as possible until renal blood flow can be established in the recipient. The present study was performed to assess the importance of the duration of the initial period of ischemia in determining subsequent function of canine kidneys and to compare the effectiveness of cooling alone, of cooling in an environment of hyperbaric oxygen, and of normothermic . . . [Full Text PDF of this Article]

Author Affiliations
ROCHESTER, MINN

From Mayo Clinic and Mayo Foundation, sections of surgical research (Dr. Hallenbeck), experimental and anatomic pathology (Dr. Shorter), clinical pathology (Dr. Owen), and medicine (Dr. Hunt). Resident in Nephrology Mayo Graduate School of Medicine (Dr. Baitz), and Resident in Surgery, (Dr. Scott).

Footnotes
Read before 22nd Annual Meeting, Central Surgical Association, Milwaukee, March 4-6, 1965.

Reprint requests to Mayo Clinic, Rochester, Minn 55902.

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