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New Method for Studying Peripheral Circulation in Man
ELLIS L. JONES, MD;
HENRY N. WAGNER, JR., MD;
GEORGE D. ZUIDEMA, MD
AMA Arch Surg. 1965;91(5):725-734.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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METHODS used in the past to study the peripheral circulation in man have included oscillometry, plethysmography, controlled walking tests, recording changes in skin temperature, methods for releasing nervous vasoconstrictor activity, angiography, and disappearance rates for radioactive substances injected into muscle.2 Despite this long list a simple, yet accurate method for studying and quantifying blood flow to the muscle mass of an extremity is still lacking. Objective means of measuring the deep circulation of an extremity and the effect of revascularization procedures have not been available.
This paper describes further studies of radioisotope scanning, using macroaggregated iodinated I131 serum albumin (Albumotope LS)* to study the regional blood flow to normal and diseased extremities.5
Methods
Macroaggregated iodinated I131 serum albumin was prepared initially from a 0.1 to 1% solution of iodinated I131 serum albumin (Albumotope) in a 0.9% sodium chloride solution, carefully adjusted to a pH of 5.5, the isoelectric
. . . [Full Text PDF of this Article]
Author Affiliations
BALTIMORE
From the departments of surgery, medicine, and radiology, The Johns Hopkins School of Medicine.
Footnotes
Read before the Annual Meeting of the North American Chapter of the International Cardiovascular Society, New York, June 19, 1965.
Reprint requests to 1617 Jefferson St, Rockville, 20852 Md (Dr. Jones).
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