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WILLIAM C. BIRTWELL, BS; FABIO GIRON, MD; WENDELL B. THROWER, MD; ULISES RUIZ, MD; HARRY S. SOROFF, MD; RALPH A. DETERLING, JR., MD

AMA Arch Surg. 1965;91(5):787-795.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Two BASIC approaches to the development of an "artificial heart" have been introduced by several groups of investigators: total replacement of the diseased heart by pumps contained within the vacated pericardial space^1-8 and intrathoracic bypass pumps which divert the flow of blood past the diseased ventricle or ventricles, thus reducing the flow work^9,10 (Fig 1). The inlet of such a pump is anastomosed to the left atrium and the outlet is anastomosed to the aorta. Inlet (mitral) and outlet (aortic) prosthetic valves must be provided to assume the function of mitral and aortic valves respectively.

A third basic approach is presented in this study (Fig 2). The prosthetic ventricle serves to reduce the pressure against which the disease ventricle must eject its stroke volume to the extent that the diseased ventricle is performing the function of an auxiliary left atrium. The pressure work of the physiologic ventricle is . . . [Full Text PDF of this Article]

Author Affiliations
BOSTON

From the Department of Surgery of the Tufts-New England Medical Center Hospitals.

Footnotes
Read before the Annual meeting of the North American Chapter of the International Cardiovascular Society, New York, June 19, 1965.

Reprint requests to 171 Harrison Ave, Boston, Mass 02111 (Dr. Soroff).

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