This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (1)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

HERBERT A. DIETZEL, MD; RICHARD H. SCHWARZ, MD

AMA Arch Surg. 1966;92(2):301-303.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IN RECENT years there has been a surge of interest in choriocarcinoma due mainly to the work of Dr. R. Hertz and M. C. Li and their associates with chemotherapeutic agents, particularly methotrexate. Hertz has reported complete remission of one to five year's duration in 47.5% of 63 patients treated with methotrexate.⁶ Some of the remainder have shown at least transient response to vinblastine sulfate, an oncolytic alkaloid. Presently work is being carried out with the primary use of dactinomycin.

The bizarre behavior of trophoblastic growths has been emphasized by many authors.^{1,2,4,5,7,8,9} This makes premature and overzealous interpretation of new therapeutic measures hazardous. In reviewing the cases of the Albert Mathieu Chorioepithelioma Registry, Brewer and associates³ found five-year survival of 21 out of 147 patients with choriocarcinoma who were treated surgically. Of these 21 patients, six had metastatic lesions.

This presentation aims to contribute two cases of . . . [Full Text PDF of this Article]

Author Affiliations
NEW BRUNSWICK, NJ; PHILADELPHIA

From the US Air Force Hospital, Keesler Air Force Base, Miss.

Footnotes
Submitted for publication Sept 14, 1965.

Opinions or conclusions contained in this paper are those of the authors and do not necessarily reflect the views or official policy of the United States Air Force.

Reprint requests to 106 Dulles Building, 3400 Spruce Street, Philadelphia, Pa 19104 (Dr. Schwarz).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?