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THOMAS C. KING, MD; J. M. ZIMMERMAN, MD

AMA Arch Surg. 1966;92(3):371-373.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IT HAS been demonstrated that anesthesia has an important effect on renal physiology.^1-7 With the increasing current interest in shock, the influence of this variable on renal blood flow in the hypovolemic animal should be reevaluated. It is the purpose of this report to describe the effect of graded hemorrhage on renal blood flow in both anesthetized and unanesthetized dogs.

Method

Six healthy mongrel dogs varying in weight from 14.5 to 23.5 kg (32 to 51.6 lb) were studied. Preliminary blood volumes were inferred following plasma volume determinations using either radio-iodinated serum albumin or Evans Blue Dye. The animals were anesthetized with sodium pentobarbital (25 mg/kg IV). Electromagnetic flowmeter probes * were implanted about the left renal artery after it had been exposed through an incision in the left flank. Extra efforts were made to minimize blood loss during the procedure. With the flowmeters in place and the connectors fixed . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO; BALTIMORE

From the departments of surgery, Kansas University Medical Center, and the Veterans Administration Hospital, Kansas City, Mo.

Footnotes
Submitted for publication Dec 4, 1965.

Reprint requests to 901 S Wolcott, Box 6998, Chicago, Ill 60680 (Dr. King).

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