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Hashimoto's Thyroiditis (Struma Lymphomatosa)Case Report of a Mother and Three Daughters, Two of Whom Are Monovular Twins
ELMER HOFFMAN, MD
AMA Arch Surg. 1966;92(6):865-867.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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THE PURPOSE of this report is to describe the occurrence of Hashimoto's thyroiditis in a mother and her three daughters, two of whom are monovular twins. All of these cases became symptomatic over a two-year period.
The familial incidence of struma lymphomatosa was first reported in 1959.1 Subsequent reports appeared in 1960,2 1961,3 1962,4,5 1963,6 and 1964.7
It is well known that various thyroid diseases such as hypothyroidism, hyperthyroidism, and nodular, nontoxic goiter may arise in members of the same family.8,9 Hashimoto's thyroiditis may be transmitted on a genetic basis.6,8 Evidence has also been presented suggesting genetic predisposition to thyroid autoimmunity.3,6,8 Hung and Winship6 report a case of a mother and daughter with Hashimoto's thyroiditis with serologic and histologic confirmation. Irvine et al3 report struma lymphomatosa in both members of two pairs of monovular twins. Zarno and Guerra7
. . . [Full Text PDF of this Article]
Author Affiliations
BALTIMORE
From the departments of surgery, The Johns Hopkins University School of Medicine and Hospital and the Sinai Hospital of Baltimore.
Footnotes
Submitted for publication Nov 17, 1965.
Reprint requests to 914 N Charles St, Baltimore, Md 21201.
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