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Postperfusion Hypervolemia After Hemodilution Cardiopulmonary Bypass
WILLIAM E. NEVILLE, MD;
RICHARD D. THOMASON, MD;
DAVID M. HIRSCH, MD
AMA Arch Surg. 1966;93(5):715-723.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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THE EFFICACY of hemodilution for cardiopulmonary bypass is well established. However, the degree to which the circulating blood volume can be diluted during whole body perfusion has not been delineated. On the one hand are the proponents of low volume nonblood oxygenator primes1,2 and on the other are the observations by Roe et al3 and Neville et al4 that a much larger system can be used without harmful sequelae. Since both methods entail postoperative infusion of the oxygenator contents to restore hemodynamics, a priori it would seem that the excess fluid in the large prime system could be injurious to the cardiac patient. However, immediate blood volume studies have consistently demonstrated a normal total blood volume with an increased plasma volume and a decreased red cell mass.5 Since normovolemia following this type of perfusion was in sharp contrast to the observations of Gadboys and Litwak7
. . . [Full Text PDF of this Article]
Author Affiliations
HINES, ILL
From the Cardiopulmonary Surgical Section, Veterans Administration Hospital, Hines, and the Department of Surgery, University of Illinois College of Medicine, Chicago.
Footnotes
Read before the 14th Scientific Meeting of the North American Chapter of the International Cardiovascular Society, Chicago, June 25, 1966.
Reprint requests to Cardiopulmonary Surgical Section, Veterans Administration Hospital, Hines, Ill 60141 (Dr. Neville).
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